Seulkee Yang, MSc


Seulkee Yang, MSc
PhD student

I am a biologist, who is passionate about electrophysiology. I received my BSc in Biology and a MSc in Neuro- and bahavioral Biology from Free University of Berlin, Germany. At Nam lab, I am dissecting the pathophysiology of Parkinson’s disease with strong emphasis on astrocyte using a wide range of methods including electrophysiology and optogenetics.

I am a biologist, who is passionate about electrophysiology. I received my BSc in Biology from Free University of Berlin, Germany, where I took my first step into Science. My research interest narrowed down to Neuroscience after conducting my thesis project at Sigrist lab. Using aging Drosophila brain as my model, I studied the utililty of Spermidine as possible anti-againg mediator. I then obtained a MSc in Biology from the same university with specialization in Neuro- and bahavioral Biology. During my master, I participated in a project at Kettenmann lab, where glia physiology is studied. This experience led me to conduct master thesis at Wolf lab to investigate the implication of autistic mouse retina in retinal function and microglial properties. At Nam lab, I am dissecting pathophysiology of Parkinson’s disease with strong emphasis on astrocyte using a wide range of methods including electrophysiology and optogenetics.


Education

UST, KIST school (Mar 2021 present)

PhD student

Free University of Berlin (Oct 2018 – Sep 2020)

MSc. Biology with specialization in Neuro- and Behavioral Biology

Free University of Berlin (Oct 2014 – Sep 2018)

BSc. Biology


Publication

  1. Chae U, Shin H, Choi N, Ji MJ, Park HM, Lee SH, Woo J, Cho Y, Kim K, Yang S, Nam MH, Yu HY, Cho IJ. Bimodal neural probe for highly co-localized chemical and electrical monitoring of neural activities in vivo. Biosensors and Bioelectronics. 2021 June, doi:10.1016/j.bios.2021.113473
  2. An H, Lee H, Yang S, Won W, Lee CJ, Nam MH. Adenovirus-induced Reactive Astrogliosis Exacerbates the Pathology of Parkinson's Disease. Exp Neurobiol. 2021 May 28. doi: 10.5607/en21013
  3. Costa A, Haage V, Yang S, Wegner S, Ersoy B, Ugursu B, Rex A, Kronenberg G, Gertz K, Endres M, Wolf SA, Kettenmann H. Deletion of muscarinic acetylcholine receptor 3 in microglia impacts brain ischemic injury. Brain Behav Immun. 2021 Jan;91:89-104. doi: 10.1016/j.bbi.2020.09.008


Technical laboratory skills

Electrophysiological recordings: Patch-clamp (cell culture and acute brain slices)

Immunohistochemistry: Retinal flat mount, brain slices and retinal paraffin sections

Fluorescence microscopy

Western blot

qPCR

ELISA

Animal behavior experiment (fly and mouse)

Data analysis using R