She received B.S. degree of biology from Konkuk University and received Ph.D. degree of neuroscience from UST. She has studied the molecular and metabolic mechanism of Alzheimer's disease through reactive astrocytes in Justin Lee's Lab. In Nam lab, she is studying molecular mechanisms of epilepsy and metabolic alterations of neurological diseases using electrophysiology and molecular biology.
Education
2015. 03 – 2021. 08 Ph.D. in Neuroscience, University of Science & Technology (UST) in Korea
- Advisor: Dr. C. Justin Lee
- Dissertation: Exploration of Alzheimer’s disease from the diagnosis and treatment to the underlying mechanisms of memory impairment
2011. 03 – 2015. 02 BA, in Life Science, Konkuk University, Seoul, South Korea
Work experience
2018. 11 – 2021. 08 Integrated course of Ph.D. program in Institute for Basic Science (IBS)
2015. 03 – 2018. 10 Integrated course of Ph.D. program in Korea Institute of Science and Technology (KIST)
2014. 03 – 2015. 02 Internship in Korea Institute of Science and Technology (KIST)
2014. 02 – 2014. 03 Internship in Korean Basic Science Institute (KBSI)
Research Interests
Identification of the role of astrocytes in neurodegenerative diseases
Pathogenesis of Alzheimer’s disease and other neurodegenerative diseases
Expertise and Speciallized Experimental Skills
Electrophysiology Slice patch, Cell patch, Sniffer patch
Molecular works Enzyme assays, Cloning, shRNA development
Histology / Immunohistochemistry
Primary cell cultures Primary neuron, Primary astrocyte, cell line managing,
Behavioral tests
Publications
Awards
Oral presentation in KIST - BSI conference (2017, Sep) _New reversible MAO-B inhibitor KDS2010 abolishes astrogliosis and memory impairment in Alzheimer’s disease model
Poster presentation at Korea Society of Neurodegeneration Disorder (KSND) (2018, March) _ PyrPeg, a Novel Two-photon Probe to Selectively Detect Aβ in Alzheimer’s Disease
Poster awards at Korea Society of Neurodegeneration Disorder (KSND), (2020, Dec): “PyrPeg, a Blood–Brain-Barrier-Penetrating Two-Photon Imaging Probe, Selectively Detects Neuritic Plaques, Not Tau Aggregates”.
Poster awards at Korean Society for Brain and Neural Sciences (KSBNS), (2021, May): “Astrocytic urea cycle impairs memory in Alzheimer’s disease”.
1st poster presentation awards at Center for cognition and sociality workshop (IBS), (2021, June): “Astrocytic urea cycle impairs memory in Alzheimer’s disease”.
Patent
Two-photon Probe and Tracer for PET Specific to Amyloid-beta Oligomers and Plaques (아밀로이드 베타 올리고머 및 플라크에 특이적인 이광자 프로브 및 PET용 추적자), 2019, Korean Patent 10-2019-0027119